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KMID : 0360220180590121103
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Journal of the Korean Ophthalmological Society
2018 Volume.59 No. 12 p.1103 ~ p.1107
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Effect of Intense Regulated Pulse Light on Thickness of Tear Film Lipid Layer and Dry Eye Syndrome
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Gil Tae-Young
Bae Gi-Hyun
Kwag Joo-Young
Hyun Joo
Choi Jin-Seok
Pak Kyu-Hong
Chung Sung-Kun
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Abstract
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Purpose: To evaluate the clinical effect of intense regulated pulse light (IRPL) and changes in tear film thickness in dry eye patients.
Methods: A retrospective study was conducted on 25 patients with Meibomian gland dysfunction who had subjective dry eye discomfort and whose tear film break-up time (TBUT) was < 10 seconds. All patients were treated with IRPL three times on days 1, 15, and 45. TBUT, Schirmer 1 test results, cornea staining score with fluorescein, ocular surface disease index (OSDI), and lipid layer thickness were measured and compared before and after the procedure.
Results: TBUT was significantly increased from 3.7 ± 1.2 s to 4.4 ± 2.1 s after IRPL (p = 0.03). Schirmer 1 test and cornea staining scores changed significantly (p < 0.01 and p = 0.01, respectively). OSDI also showed a statistically significant improvement from 39.5 ± 17.5 points to 30.4 ± 18.7 points (p = 0.01). However, no significant difference in lipid layer thickness was observed (p = 0.49).
Conclusions: IRPL is an effective treatment modality to improve TBUT, Schirmer 1 test scores, cornea staining scores, and subjective dry eye symptoms.
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KEYWORD
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Dry eye syndrome, Intense pulse light (IPL), Intense regulated pulse light (IRPL), Lipid layer thickness (LLT), Lipiview
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